surgicryl – PDO (Polydioxanone)Description
PDO is a sterilised monofilament synthetic absorbable suture.
The copolymer is prepared by in either undyed form or dyed with Violet.
The undyed material is completely clear and not opaque as in the undyed versions of both polyglycolic acid and SURGICRYL 910 (Polyglactin 910) sutures.
It is extruded into monofilaments of various diameters then annealed (heat treated) under tension to give the desired handling characteristics. The material is then cut to length and packaged, Limited the
material is tested then attached to needle(s).
PDO is available in gauge sizes Metric O.7 (6-0) – 5.0 (USP 2) in lengths of 45 cm, to 150 cm, with needles attached.
PDO Absorption Profile
PDO offers significantly longer strength retention than other absorbable sutures allowing its use in areas where previously only a non-absorbable could be considered.
Strength retention Profile
|3-0 & larger||4-0 & smaller|
|14 days –||75% of original strength remains||60%of original strength remains|
|28 days –||70% of original strength remains||50%of original strength remains|
|42 days –||50% of original strength remains||35%of original strength remains|
Loss of tensile strength
The material is for use in surgical operations on the human body where an absorbable suture or ligature is required. These suture are particularly useful where the combination of an absorbable suture and extended wound support (up to six weeks) is desirable
At 14 days, SURGICRYL 910 retains approximately 75% of its initial strength. PDO sutures also retain approximately 75% of their original strength at 14 days.
At 28 days post implantation, both SURGICRYL 910 no longer retain significant wound support and provide less than 10% of their original value, whereas PDO sutures retain between70 – 50% of its original strength.Even at 42 days, PDO sutures retain between 50 -35% of its original strengt
One feature of PDO (Polydioxanone), which makes it different from the first generation synthetic absorbables, is its basic flexibility. Neither polyglycolic acid filaments nor polyglactin 910 are sufficiently flexible to enable them to be used as monofilament sutures, except in gauges 9-0 and 10-0.
The material is for use in surgical operations on the human body where an absorbable suture or ligature is required. These suture are particularly useful where the combination of an absorbable suture and extended wound support (up to six weeks) is desirab
|Strong monofilament||Finer gauges can be used||Less material is implanted, fewer problems from reactions to foreign bodies|
|Synthetic||Predictable absorption profile||No concerns about residual material causing problems|
|Absorbable||No foreign bodies left||No concerns over long term problems|
|Inert||Minimal tissue reactions||Confidence regarding wound healing|
|Monofilament||Smooth passage through tissue, no bacterial harbours||Minimal damage to tissue, no risk of
infection being introduced or prolonged
|Clinical evidence available||Proven results in vivo and in vitro||Confidence in using a proven product|
|Retains strength for over 6 weeks||Can be used in fascial tissue||Can replace non-absorbables, reducing the risk of suture sinus. Creates fewer problems for the patient and surgeon|
Sterilisation is by the Ethylene Oxide process.
Abdominal Closure, Colon, Skin