SURGICRYL MONOFILAMENT(Polydioxanone)

surgicryl  – PDO (Polydioxanone)Description

 

PDO is a sterilised monofilament synthetic absorbable suture.

 

The copolymer is prepared by in either undyed form or dyed with Violet.

 

The undyed material is completely clear and not opaque as in the undyed versions of both polyglycolic acid and SURGICRYL 910 (Polyglactin 910) sutures.

 

It is extruded into monofilaments of various diameters then annealed (heat treated) under tension to give the desired handling characteristics. The material is then cut to length and packaged, Limited the

material is tested then attached to needle(s).

PDO is available in gauge sizes Metric O.7 (6-0) – 5.0 (USP 2) in lengths of 45 cm, to 150 cm, with needles attached.

PDO Absorption Profile

 

PDO offers significantly longer strength retention than other absorbable sutures allowing its use in areas where previously only a non-absorbable could be considered.

Strength retention Profile

 

	3-0 & larger	4-0 & smaller
14 days –	75% of original strength remains	60%of original strength remains
28 days –	70% of original strength remains	50%of original strength remains
42 days –	50% of original strength remains	35%of original strength remains

 

Loss of tensile strength

Indications

 

The material is for use in surgical operations on the human body where an absorbable suture or ligature is required. These suture are particularly useful where the combination of an absorbable suture and extended wound support (up to six weeks) is desirable

At 14 days, SURGICRYL 910 retains approximately 75% of its initial strength. PDO sutures also retain approximately 75% of their original strength at 14 days.

 

At 28 days post implantation, both SURGICRYL 910 no longer retain significant wound support and provide less than 10% of their original value, whereas PDO sutures retain between70 – 50% of its original strength.Even at 42 days, PDO sutures retain between 50 -35% of its original strengt

PDO Advantages

 

One feature of PDO (Polydioxanone), which makes it different from the first generation synthetic absorbables, is its basic flexibility. Neither polyglycolic acid filaments nor polyglactin 910 are sufficiently flexible to enable them to be used as monofilament sutures, except in gauges 9-0 and 10-0.

Indication

The material is for use in surgical operations on the human body where an absorbable suture or ligature is required. These suture are particularly useful where the combination of an absorbable suture and extended wound support (up to six weeks) is desirab

Summary: PDO

 

FEATURE	ADVANTAGE	BENEFIT
Strong monofilament	Finer gauges can be used	Less material is implanted, fewer problems from reactions to foreign bodies
Synthetic	Predictable absorption profile	No concerns about residual material causing problems
Absorbable	No foreign bodies left	No concerns over long term problems
Inert	Minimal tissue reactions	Confidence regarding wound healing
Monofilament	Smooth passage through tissue, no bacterial harbours	Minimal damage to tissue, no risk of infection being introduced or prolonged
Clinical evidence available	Proven results in vivo and in vitro	Confidence in using a proven product
Retains strength for over 6 weeks	Can be used in fascial tissue	Can replace non-absorbables, reducing the risk of suture sinus. Creates fewer problems for the patient and surgeon

Sterilisation

 Sterilisation is by the Ethylene Oxide process.

Surgical uses

Abdominal Closure, Colon, Skin